High Prevalence of DMD and R&D of New Therapies for DMD Treatment to Augment Growth of Duchenne Muscular Dystrophy (DMD) Treatment Market

 


Duchenne Muscular Dystrophy (DMD) is a rare hereditary disease that affects the muscles and the connective tissue of the body. This condition is usually identified through skin tests and in more severe cases, it can be detected through MRI. The symptoms include drooping eyelids, decreased muscle bulk, weak pulse, and slow heart rate. The cause of this disease is not yet known but it is believed to be due to genetic differences, abnormalities in the nervous system, and infection.

Market Dynamics

High prevalence of DMD is expected to propel growth of the Duchenne muscular dystrophy (DMD) treatment market. For instance, according to the study, ‘Global epidemiology of Duchenne muscular dystrophy: an updated systematic review and meta-analysis’ published in June 2020, in BMC,  the pooled global prevalence of DMD was 7.1 cases per 100,000 males and 2.8 cases per 100,000 in the general population, while the pooled global birth prevalence of DMD was 19.8 per 100,000 live male births.

R&D of new therapies for DMD treatment is expected to offer lucrative growth opportunities for players in the Duchenne muscular dystrophy (DMD) treatment market. For instance, in January 2021, Pfizer, Inc. announced that the first boy was dosed in a Phase 3 trial that evaluated the company’s gene therapy, PF-06939926, in treating Duchenne muscular dystrophy. Similarly, in January 2021, Sarepta Therapeutics, Inc. announced top-line results from Part 1 of Study SRP-9001-102 to evaluate the safety, efficacy and tolerability of a single dose of SRP-9001 for the treatment of DMD.

Moreover, adoption of partnership strategies is also expected to offer lucrative growth opportunities for players in the market. For instance, in January 2021, Capricor Therapeutics, a clinical-stage biotechnology company, partnered with Lonza Group for the development of CAP-1002, its clinical asset using allogeneic cardiosphere-derived cells technology for the treatment of Duchenne muscular dystrophy.

Competitive Analysis

Major players operating in Duchenne muscular dystrophy (DMD) treatment market include, SUMMIT Therapeutics Plc., Sarepta Therapeutics, Inc., PTC Therapeutics, BioMarin Pharmaceuticals Incorporated, Italfarmaco Group, Sarepta Therapeutics, Pfizer Inc., Pharmacia & Upjohn LLC, and others.

Major players operating in Duchenne muscular dystrophy (DMD) treatment are focused on approval and launch of new products to expand their product portfolio. For instance, in October 2020, The Italfarmaco Group reported that The U.S. Food and Drug Administration (FDA) granted a Rare Pediatric Disease designation to Givinostat, its proprietary histone deacetylase (HDAC) inhibitor, for the treatment of Duchenne muscular dystrophy.


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